The evolutionarily conserved target of rapamycin complex 1 (TORC1) is a master regulator of cell growth and metabolism. In mammals, growth factors and cellular energy stimulate mTORC1 activity through ...
Cells and organisms need to integrate information from the environment to ensure that they only grow when conditions are favourable. The highly conserved Ser/Thr protein kinase target of rapamycin ...
Each protein or peptide consists of a linear sequence of amino acids. The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C) ...
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