Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

As animals and people age, there are changes in the genome. Telomeres, the protective ends of chromosomes, get shorter as cells continue to divide; some cells will pick up mutations in their genomes ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to ...

A study reveals how the essential red blood cell transcription factor KLF1 recognizes DNA. Using precise measurements in test ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

Scientists discovered that the first 100 base pairs of human genes are unusually prone to mutations, especially during the ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new wave of research is forcing a rethink, showing that the three-dimensional ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...