Biphenomycins, natural products derived from bacteria, show excellent antimicrobial activity, but have long remained out of ...

Gram-negative bacteria, notorious for their intrinsic and acquired resistance mechanisms, pose a significant threat to public health. The emergence of ...

Northwestern Medicine investigators have identified issues with most genomic sequence data for the Neisseria gonorrhoeae ...

Middle-ear infections caused by Gram-negative bacteria remain among the most common pediatric illnesses worldwide.

Eustachian tube dysfunction often determines whether a routine ear infection clears quickly or develops into a persistent ...

Scientists have released new images showing, in incredible detail, antibiotics defeating disease-causing bacteria by piercing the microbes' membranes and infiltrating their innards. The antibiotics, ...

An untreated E.coli bacterium (top); a bacterium after 90 minutes of being exposed to polymyxin B (bottom). Credit: Nature Microbiology Our bodies are a constant battlefield between pathogens and our ...

Physicians have relied on a class of antibiotics called polymyxins to fight potentially life-threatening Gram-negative bacterial infections for more than 80 years. These drugs are typically reserved ...

Lipopolysaccharide (LPS) from Gram-negative bacteria has been one of the most studied pathogen-associated molecular patterns triggering rapid inflammatory reactions. However, evidence shows that not ...